Clinical Research

Detect changes in neurological and psychiatric symptoms faster, more easily, and more objectively through speech with the help of natural language processing and artificial intelligence.

Work with us

Backed by clinical evidence

Linguistic features identify Alzheimer’s disease in narrative speech

Detecting Alzheimer’s disease

Analysis of spontaneous speech data elicited through Cookie Theft picture description (1-5 minute samples) from 240 people probable AD category and 233 healthy controls. Linguistic and acoustic variables used to train a machine learning classifier to distinguish between the groups, with 82% accuracy.

Fraser, K. C., Meltzer, J. A., & Rudzicz, F. (2016). Linguistic features identify Alzheimer’s disease in narrative speech. Journal of Alzheimer's Disease, 49(2), 407-422.
Using Linguistic Features Longitudinally to Predict Clinical Scores for Alzheimer's Disease and Related Dementias

Predicting MMSE for AD monitoring

A temporal Bayes network trained on 182 lexicosyntactic, 210 acoustic, and 85 semantic features extracted from 393 spontaneous speech samples elicited through Cookie Theft picture description can predict MMSE scores with a mean absolute error of 3.8, comparable to within-subject interrater (clinician) standard deviation of 3.9 to 4.8.

Yancheva, M., Fraser, K., & Rudzicz, F. (2015). Using Linguistic Features Longitudinally to Predict Clinical Scores for Alzheimer's Disease and Related Dementias.
Automated classification of primary progressive aphasia subtypes from narrative speech transcripts

Subtyping primary progressive aphasia

Syntactic and semantic features were automatically extracted from transcriptions of narrative speech for three groups: semantic dementia (SD), progressive nonfluent aphasia (PNFA), and healthy controls. Machine learning classifiers trained on these features were able to distinguish between the three participant groups with up to 100% accuracy.

Fraser, K.C., Meltzer, J.A., Graham, N.L., Leonard, C., Hirst, G., Black, S.E., & Rochon, E. (2014). Automated classification of primary progressive aphasia subtypes from narrative speech transcripts. Cortex, 55, 43-60.

Our technology

Drug development in neuroscience is hampered by insensitive clinical scales which may not detect subtle changes in symptoms. By extracting over 550 features of speech and language, Winterlight Labs’ technology can measure fine-grained changes that traditional assessments cannot. Our algorithms then use these features to classify heterogeneous disease populations into subgroups, track change over time, and detect response to treatment. Winterlight’s speech assessment is deployed in a dozen clinical studies spanning Alzheimer’s disease, frontotemporal dementia, depression, bipolar disorder, and schizophrenia.

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Unique benefits

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Ease of use

Traditional endpoints are complex, stressful for patients, require specialized training to administer consistently and are challenging to deliver remotely. Our technology is flexible and simple to use. It can be administered by research staff in traditional clinic settings, while also serving as a higher frequency, digital patient reported outcome (PRO) in decentralized trial designs.

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Automatic and objective scoring

The assessment can be completed objectively across patients and administrators. Standard cognitive assessments include components which are subjectively scored and often too coarse. We analyze hundreds of linguistic cues and vocal biomarkers to detect Alzheimer’s disease and other conditions with accuracies between 82% and 100%, as reported in our peer-reviewed academic studies.

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Discover Insights

Our approach goes beyond analyzing the acoustic properties of speech, and also includes the linguistic components of speech, such as word choice, sentence structure, and coherence of ideas to produce a set of over 550 variables. These variables can be grouped into composite metrics such as word-finding difficulty, syntactic complexity, lexical richness, discourse mapping and more.

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Flexible Implementation

We recognize that every clinical development program is unique and so we offer different ways to work with Winterlight as part of your clinical research program. We have developed our own Winterlight Assessment App with customizable tasks that can be used to collect speech data throughout the study, or we can integrate into existing data collection tools via API. We also have the capability to retrospectively analyze data that has been previously collected by other means.

Publications

HEAR-MHE study: Automated speech analysis identifies minimal hepatic encephalopathy and may predict future overt hepatic encephalopathy

Bloom P.P., Fisher C.J., Tedesco N., Kamdar N., Garrido-Trevino L., Robin J., Asrani S.K., Lok A.S. (2024)

Hepatology.

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Analytical validation of a novel quality assurance approach for COAs in Alzheimer’s Disease clinical trials

Newsome, R.N., Kindellan R., Fidalgo C., Simpson W. (2024)

ISCTM 2024 Autumn Conference.

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Digital remote assessment of speech acoustics in cognitively unimpaired adults: feasibility, reliability and associations with amyloid pathology

van den Berg R., de Boer C., Zwan M.D., Jutten R.J., van Liere M., van de Glind M-C.A.B.J., Dubbelman M.A., Schlüter L.M., van Harten A.C., Teunissen C.E., van de Giessen E., Barkhof F., Collij L.E., Robin J., Simpson W., Harrison J.E., van der Flier W.M., Sikkes S.A.M. (2024)

Alzheimer's Research & Therapy.

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Speech characteristics and their association with neuroimaging and CSF biomarkers of AD pathology

Simpson W., Spilka M., Xu M., Robin J. (2024)

Alzheimer's Association International Conference (AAIC).

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Robustness and generalizability of a speech- based digital biomarker derived from recordings of the Clinical Dementia Rating (CDR) interview

Spilka M., Xu M., Toth B., Hashemifar S., Amora R., Robin J., Teng E., Monteiro C., Simpson W. (2024)

Alzheimer's Association International Conference (AAIC).

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Automated, Objective Speech and Language Markers of Longitudinal Changes in Psychosis Symptoms

Tang S.X., Spilka M.J., John M., Birnbaum M.L., Saito E., Berretta S.A., Behbehani L.M., Liberman M.Y., Malhotra A.K., Kane J.M., Simpson W. (2024)

medRxiv.

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Computational speech markers of negative symptoms show evidence of being robust to antipsychotic dose and extrapyramidal symptoms in schizophrenia

Spilka M.J., Robin J., Nikzad A.H., Behbehani L., Berretta S., Xu M., Kane J.M., Simpson W., Tang S.X. (2024)

PsyArXiv.

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Assessing and Monitoring Clinical Severity in Depressive Disorders Using Automated Speech Analysis

Spilka M.J., Xu M., Tang S.X., Behbehani L., Robin J., Simpson W. (2024)

American Society of Clinical Psychopharmacology (ASCP) 2024 Annual Meeting.

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Zero-Shot Multi-Lingual Speaker Verification in Clinical Trials

Akram A., Stanojevic M., Ehghaghi M., Novikova J. (2024)

arXiv.

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Computational speech & language features for within- & between-subject symptom characterization in first-episode psychosis

Spilka M., Yeung A., Xu M., Jebanesan B., Khan W., Ahmed S., Simpson W., Robin J., Naeem F. (2024)

Schizophrenia International Research Society 2024 Annual Congress.

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Linguistic changes in neurodegenerative diseases relate to clinical symptoms

Gumus M., Koo M., Studzinski C.M., Bhan A., Robin J., Black S.E. (2024)

Frontiers in Neurology.

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Leveraging speech production as a physiological marker of cognitive decline: Demonstration of the role of timing and acoustic changes

Sorinas J., Huynh M.T.D., Hannesdottir K., Robin J., Simpson W., Coello N., Caputo A., Riviere M.-E., Curcic J. (2024)

International Conference on Alzheimer’s and Parkinson’s Diseases and related neurological disorders (AD/PD 2024).

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Towards fully automated rating scale review: Identifying speech feature signature for administration variances in CDR interview during Alzheimer’s Disease clinical trials

Newsome R.N., Kindellan R., Fidalgo C., Simpson W. (2024)

International Society for CNS Clinical Trials and Methodology (ISCTM) 20th Annual Meeting.

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Cognitive components of aging-related increase in word-finding difficulty

Wei H.T., Kulzhabayeva D., Erceg L., Robin J., Hu Y.Z., Chignell M., Meltzer J.A. (2024)

Aging, Neuropsychology, and Cognition.

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Detecting bulbar amyotrophic lateral sclerosis (ALS) using automatic acoustic analysis

Simmatis L.E.R., Robin J., Spilka M.J., Yunusova Y. (2024)

BioMedical Engineering OnLine.

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Validation of automated pipeline for the assessment of a motor speech disorder in amyotrophic lateral sclerosis (ALS)

Simmatis L., Robin J., Pommée T., McKinlay S., Sran R., Taati N., Truong J., Koyani B., Yunusova Y. (2023)

Digital Health.

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Generalizability and Robustness of Large Language Models Detecting Alzheimer’s Disease from Speech.

Novikova J. (2023)

GenBench at EMNLP (Empirical Methods in Natural Language Processing) International Conference.

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How Much Speech Data Is Needed for Tracking Language Change in Alzheimer’s Disease? A Comparison of Random Length, 5-Min, and 1-Min Spontaneous Speech Samples.

Petti U., Baker S., Korhonen A., Robin J. (2023)

Digital Biomarkers.

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Robustness and generalizability of a speech based composite score for measuring disease progression in AD.

Spilka M., Xu M., Robin J., Simpson W. (2023)

Clinical Trials on Alzheimer’s Disease (CTAD) Conference.

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Development of a speech-based composite score for remotely quantifying language changes in frontotemporal dementia

Robin J., Xu M., Kaufman L., Simpson W., McCaughey S., Tatton N., Wolfus C., Ward M. (2023)

Cognitive and Behavioral Neurology.

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Longitudinal tracking of speech changes in ALS using a novel remote assessment.

Simmatis L., Robin J., Spilka M., Yunusova Y. (2023)

22nd Annual Meeting of the Northeast ALS Consortium.

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PROSA—a multicenter prospective observational study to develop low-burden digital speech biomarkers in ALS and FTD.

Tröger J., Baltes J., Baykara E., Kasper E., Kring M., Linz N., Robin J., Schäfer S., Schneider A., Hermann A. (2023)

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration.

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Speech Changes in Neurodegenerative Diseases Relate to Clinical Outcomes

Gumus M., Koo M., Bhan A., Robin J., Black S.E. (2023)

Alzheimer's Association International Conference.

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Natural Speech as a Digital Biomarker in Preclinical Alzheimer’s Disease: Usability of a Remote Burst Speech Assessment.

van den Berg R.L., Alzheimer Center Amsterdam (2023)

Alzheimer's Association International Conference.

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Automated detection of progressive speech changes in early Alzheimer's disease.

Robin J., Xu M., Balagopalan A., Novikova J., Kahn L., Oday A., Hejrati M., Hashemifar S., Negahdar M., Simpson W., Teng E. (2023)

Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring.

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Evaluating the utility of daily speech assessments for monitoring depression symptoms.

Gumus M., DeSouza D.D., Xu M., Fidalgo C., Simpson W., Robin J. (2023)

Digital Health.

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Computational linguistic analysis of speech tasks indexes symptom severity and change in Arabic-speaking individuals with schizophrenia.

Spilka M.J., Xu M., Robin J., Simpson W. (2023)

American Society for Clinical Psychopharmacology (ASCP) Meeting.

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Do motor symptoms and antipsychotic medications influence the digital speech assessment of negative symptoms in schizophrenia spectrum disorders?

Spilka M.J., Robin J., Nikzad A., Behbehani L., Beretta S., Xu M., Simpson W., Tang S.X. (2023)

Schizophrenia International Research Society.

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Computational speech and language biomarkers for psychosis symptoms during acute hospitalization.

Tang S.X., Spilka M.J., Berretta S., Behbehani L., Birnbaum M., Saito E., Costakis A., Robin J., John M., Liberman M., Simpson B., Kane J.M. (2023)

Schizophrenia International Research Society.

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Detecting bulbar amyotrophic lateral sclerosis (ALS) using automatic acoustic analysis.

Simmatis L., Robin J., Yunusova Y. (2023)

International Conference on Aging, Innovation, and Rehabilitation.

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Task-specific sensitivity of digital speech assessment to symptom severity in first-episode psychosis.

Spilka M., Yeung A., Xu M., Jebanesan B., Khan W., Ahmed S., Simpson W., Robin J., Naeem F. (2023)

Society of Biological Psychiatry.

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Speech biomarkers in mood disorders: a cross-sectional study.

de Azevedo Cardoso T., Rakovski C., Kapczinski F., Simpson W., Robin J. (2023)

Society of Biological Psychiatry.

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Speech phenotypes in cognitively healthy participants at risk of developing Alzheimer’s disease.

Sorinas J., Robin J., Simpson W., Curcic J., Hannesdottir K. (2023)

International Conference on Alzheimer's and Parkinson's Diseases (ADPD).

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The generalizability of longitudinal changes in speech before Alzheimer’s Disease diagnosis.

Petti U., Baker S., Korhonen A., Robin J. (2023)

Journal of Alzheimer's Disease.

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Clinical validation of a novel speech assessment app in amyotrophic lateral sclerosis (ALS).

Simmatis L.E.R., Robin J., Truong J., Pommee T., Koyani B., Yunusova Y. (2023)

International Society for CNS Clinical Trials and Methodology.

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Assessments of ADAS-Cog administration quality are comparable across expert and non-expert reviewers.

Kindellan R., Newsome R., Fidalgo C., Robin J. (2023)

International Society for CNS Clinical Trials and Methodology.

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Exploring the analytical validity of the Winterlight assessment app – a novel, home-based speech assessment tool – in ALS.

Simmatis L., Robin J., Pommee T., Khoyani B., Yunusova Y. (2022)

33rd International Symposium on ALS/MND.

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Validation of an objective, speech-based object content score for measuring disease progression in AD.

Robin J., Xu M., Detke, M., Simpson W. (2022)

Clinical Trials in Alzheimer's Disease.

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Accuracy of automated scoring of word recall assessments.

Kindellan, R., Sirotkin, S., Xu, M., Fidalgo, C., Simpson, W., Robin, J. (2022)

Clinical Trials in Alzheimer's Disease.

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Cost-effective Models for Detecting Depression from Speech.

Tasnim, M., Novikova, J. (2022)

IEEE International Conference on Machine Learning and Applications (ICMLA).

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Slow speech can identify patients with Hepatic Encephalopathy.

Bloom P.P., Robin J., Lok A.S.F. (2022)

American Association for the Study of Liver Diseases: The Liver Meeting.

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Multi-modal deep learning system for depression and anxiety detection.

Diep, B., Stanojevic, M., Novikova, J. (2022)

PAI4MH workshop at NeurIPS.

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Digital Speech Recording for Quantifying Language Deficit in Brain Tumor Patients: Measuring the Subclinical

Selner A., Robin J., Khan. O.K. (2022)

Congress of Neurological Surgeons.

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Analytical validation of automatic speech recognition tools used for voice biomarker development.

Kindellan R., Xu M., Ruan J., Sirotkin S., Robin J. (2022)

International Society for CNS Clinical Trials and Methodology.

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Impact of Environmental Noise on Alzheimer’s Disease Detection from Speech: Should You Let a Baby Cry?

Novikova, J. (2022)

COLING Workshop: The 8th Workshop on Noisy User-generated Text (W-NUT).

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Data-driven Approach to Differentiating between Depression and Dementia from Noisy Speech and Language Data.

Ehghaghi, M., Rudzicz, F., Novikova, J. (2022)

COLING Workshop: The 8th Workshop on Noisy User-generated Text (W-NUT).

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Description of the Method for Evaluating Digital Endpoints in Alzheimer Disease Study: Protocol for an Exploratory, Cross-sectional Study.

Curcic J., Vallejo V., Sorinas J., Sverdlov O., Praestgaard J., Piksa M., Deurinck M., Erdemli G., Bugler M., Tarnanas I., Taptiklis N., Cormack F., Anker R., Masse F., Souillard-Mandar W., Intrator N., Molcho L., Madero E., Bott N., Chambers M., Tamory J., Shulz M., Fernandez G., Simpson W., Robin J., Snaedal JG., Cha J., Hannesdottir K. (2022)

JMIR Research Protocols.

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Benchmarking Prognostic Longitudinal Machine Learning Models of Alzheimer’s Disease Using Speech Features.

Ehghaghi, M., Novikova, J., Sett, A., Hejrati, M., Robin, J., Teng, E., Hashemifar, S. (2022)

Applications of Medical AI (AMAI).

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Characterizing progressive speech changes in prodromal-to-mild Alzheimer’s disease using natural language processing.

Robin J., Xu M., Balagopalan A., Novikova J., Kahn L., Oday A., Hejrati M., Hashemifar S., Negahdar M., Simpson W., Teng E. (2022)

Alzheimer's Association International Conference.

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Acoustic and Linguistic Features of Impromptu Speech and Their Association With Anxiety: Validation Study.

Teferra B.G., Borwein S., DeSouza D.D., Simpson W., Rheault L., Rose J. (2022)

JMIR Mental Health.

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Who does what to whom? graph representations of action-predication in speech relate to psychopathological dimensions of psychosis.

Nikzad A.H., Cong Y., Berretta S., Hansel K., Cho S., Pradhan S., Behbehani L., DeSouza D.D., Liberman M.Y., Tang S.X. (2022)

Schizophrenia.

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DEPAC: A Corpus for Depression and Anxiety Detection from Speech.

Tasnim, M., Ehghaghi, M., Diep, B., Novikova, J. (2022)

Proceedings of CLPsych.

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The burgeoning role of speech and language assessment in schizophrenia spectrum disorders.

DeSouza D.D., Tang S.X., Danilewitz M. (2022)

Psychological Medicine.

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Predicting Depression Scores using Digital Speech Measures Collected at High-Frequency

DeSouza D.D., Gumus M., Xu M., Fidalgo C., Simpson W., Robin J. (2022)

Society of Biological Psychiatry (SOBP) Annual Meeting.

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Predicting Treatment Outcomes with Computational Speech Features in Hospitalized Patients with Schizophrenia

Tang S.X., DeSouza D.D., Berretta S., John M., Cong Y., Birnbaum M.L., Costakis A., Saito E., Kane J., Simpson B. (2022)

Schizophrenia International Research Society.

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Development of a novel digital speech composite measure for Frontotemporal Dementia

Robin J., Xu M., Kaufman L.D., Simpson W., McCaughey S., Wolfus C., Jackson S., Ward M. (2022)

American Academy of Neurology Annual Meeting.

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Association Between Speech Characteristics And Cortical [18F]GTP1 Tau PET Tau Levels In Prodromal-To-Mild Alzheimer’s Disease

Robin J., Xu M., Balagopalan A., Novikova J., Hashemifar S., Oday A., Kahn L., Hejrati M., Amora R., Bohorquez S.S., Simpson W., Teng E. (2022)

Alzheimer's & Parkinson's Diseases Conference.

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Characterizing Depressive Symptom Fluctuations using Automated Speech Assessment: a Remote Feasibility Study

DeSouza D.D., Gumus M., Fidalgo C., Simpson W., Robin J. (2022)

International Society for CNS Clinical Trials and Methodology.

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Using Digital Speech Assessments to Detect Early Signs of Cognitive Impairment.

Robin J., Xu M., Kaufman L.D., Simpson W. (2021)

Frontiers in Digital Health.

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Natural Language Processing as an Emerging Tool to Detect Late-Life Depression.

DeSouza D.D., Robin J., Gumus M., Yeung A. (2021)

Frontiers in Psychiatry.

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Fluency in spontaneous speech predicts individual variance in executive function among seniors.

Spencer K.A., Robin J., Xu M., Rose M.K., Bialystok E., Meltzer J.A. (2021)

Alzheimer's Association International Conference.

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Differential speech and language characteristics across neurodegenerative disorders.

Robin J., Xu M., DeSouza D.D., Gupta A.S., Kaufman L.D., Simpson W. (2021)

Alzheimer's Association International Conference.

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Hepatic encephalopathy is associated with slow speech on objective assessment.

Bloom P.P., Robin J., Xu M., Arvind A., Daidone M., Gupta A., Chung R.T. (2021)

The American Journal of Gastroenterology.

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Correlating natural language processing and automated speech analysis with clinician assessment to quantify speech-language changes in mild cognitive impairment and Alzheimer’s dementia.

Yeung A., Iaboni A., Rochon E., Lavoie M., Santiago C., Yancheva M., Novikova J., Xu M., Robin J., Kaufman L.D., Mostafa F. (2021)

Alzheimer's Research & Therapy.

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Psychometric Approach to Speech Feature Analysis as an Objective Measure of Anxiety.

DeSouza D., Xu M., Fidalgo C., Robin J., Simpson B. (2021)

Society of Biological Psychiatry (SOBP) Annual Meeting.

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Comparing Pre-trained and Feature-Based Models for Prediction of Alzheimer's Disease Based on Speech

Balagopalan A., Eyre B., Robin J., Rudzicz F., Novikova J. (2021)

Frontiers in Aging Neuroscience.

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Variation in speech and language variables based on demographic factors.

Robin J., Xu M., Simpson W. (2021)

International Society for CNS Clinical Trials and Methodology.

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Analytical and clinical validation of digital language assessments.

Robin J., Xu M., Simpson W., Novikova J. (2021)

International Society for CNS Clinical Trials and Methodology.

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Augmenting BERT Carefully with Underrepresented Linguistic Features

Balagopalan A., Novikova J. (2020)

Machine Learning for Health Workshop at NeurIPS 2020.

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Remote assessment of speech and language changes in Primary Progressive Aphasia (PPA) and behavioral variant Frontotemporal Dementia (bvFTD).

Robin J., Xu M., Kaufman L.D., Hagey M., Paul R., Siddiqui O., Ward M., Simpson W. (2020)

Clinical Trials on Alzheimer’s Disease.

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Evaluation of speech-based digital biomarkers for Alzheimer’s Disease.

Robin J., Kaufman L.D., Simpson W. (2020)

Clinical Trials on Alzheimer’s Disease.

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Evaluation of Speech-Based Digital Biomarkers: Review and Recommendations.

Robin J., Harrison J.E., Kaufman L.D., Rudzicz F., Simpson W., Yancheva M. (2020)

Digital Biomarkers, 99–108.

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Fantastic Features and Where to Find Them: Detecting Cognitive Impairment with a Subsequence Classification Guided Approach

Eyre B., Balagopalan A., Novikova J. (2020)

W-NUT Workshop on Noisy User-generated Text at EMNLP 2020.

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Hepatic Encephalopathy is Associated with a Distinct Speech Pattern.

Bloom P.P., Arvind A., Daidone M., Robin J., Xu M., Gupta A.S., Chung R.T. (2020)

American Association for the Study of Liver Diseases: The Liver Meeting.

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Gathering normative speech data for depression research remotely, using online task marketplaces.

Fidalgo C., Xu M., Balagopalan A., Robin J., Kaufman L.D., Simpson W. (2020)

International Society for CNS Clinical Trials and Methodology.

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A comparison of clinician assessment of speech versus automated speech analysis in Mild Cognitive Impairment and Alzheimer’s Dementia.

Yeung A., Iaboni A., Rochon E., Lavoie M., Santiago C., Yancheva M., Novikova J., Xu M., Robin J., Kaufman L.D., Mostafa F. (2020)

Alzheimer’s Association International Conference.

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Quality comparison of remote vs. in-person digital speech assessment for dementia.

Robin J., Novikova J., Sirotkin S., Yancheva M., Kaufman L.D., Simpson W. (2020)

Alzheimer’s Association International Conference.

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Comparing longitudinal changes in speech-based digital measures in cognitively healthy, possible cognitive impairment, and MCI/AD individuals.

Robin J., Xu M., Kaufman L.D., Simpson W. (2020)

Alzheimer’s Association International Conference.

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To BERT or Not To BERT: Comparing Speech and Language-based Approaches for Alzheimer's Disease Detection

Balagopalan A., Eyre B., Rudzicz F., Novikova J. (2020)

Proceedings of INTERSPEECH 2020.

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Assessment of ataxia using natural language processing and computational analysis of speech.

Simpson W., Kaufman L.D., Balagopalan A., Khan N.C., Gupta A.S. (2020)

Ataxia Investigators Meeting.

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Tracking changes in cognition in Mild Cognitive Impairment and Alzheimer’s Disease over a 6-month period using a speech-based digital biomarker.

Robin J., Simpson W., Kaufman L.D. (2020)

International Society for CNS Clinical Trials and Methodology.

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Pause-Focussed Sequential Modelling for Predicting Cognitive Impairment on Limited Data

Eyre B., Balagopalan A., Novikova J. (2019)

Machine Learning for Health Workshop at NeurIPS 2019.

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Evaluating a method for automatic and objective scoring of verbal response for the Montreal Cognitive Assessment (MoCA).

Kaufman L.D., Balagopalan A., Novikova J., Mostafa F. (2019)

Clinical Trials on Alzheimer’s Disease.

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Early development of a unified, speech and language composite to assess the clinical severity of Frontotemporal Lobar Degeneration (FTLD).

Balagopalan A., Kaufman L.D., Novikova J., Siddiqui O., Paul R., Ward M., Simpson W. (2019)

Clinical Trials on Alzheimer’s Disease.

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Cross-Language Aphasia Detection using Optimal Transport Domain Adaptation

Balagopalan A., Novikova J., McDermott M. B. A., Nestor B., Naumann T., Ghassemi M. (2019)

Machine Learning for Health Workshop at NeurIPS 2019.

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Comparing a speech-based digital biomarker to the Montreal Cognitive Assessment (MoCA) for tracking cognition over a 6-month period in a naturalistic cohort of older adults.

Simpson W., Balagopalan A., Kaufman L.D., Yancheva M. (2019)

Clinical Trials on Alzheimer’s Disease.

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Lexical Features Are More Vulnerable, Syntactic Features Have More Predictive Power

Novikova J., Balagopalan A., Shkaruta K., Rudzicz F. (2019)

W-NUT Workshop on Noisy User-generated Text at EMNLP 2019.

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Use of a voice-based digital biomarker in patients with depression.

Simpson W., Balagopalan A., Kaufman L.D., Yeung A., Butler A (2019)

International Society for CNS Clinical Trials and Methodology.

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Utility of speech-based digital biomarkers for evaluating disease progression in clinical trials of Alzheimer’s disease.

Simpson W., Kaufman L.D., Detke M., Lynch S., Butler A., Dominy A. (2019)

Alzheimer’s Association International Conference.

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Comparison of a speech-based digital biomarker with the MoCA in a naturalistic cohort of seniors.

Simpson W., Kaufman L.D., Balagopalan A., Novikova J. (2019)

Alzheimer’s Association International Conference.

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Using acoustic and linguistic markers from spontaneous speech to predict scores on the Montreal Cognitive Assessment (MoCA).

Balagopalan A., Yancheva M., Novikova J., Simpson W. (2019)

Society of Biological Psychiatry.

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Impact of ASR on Alzheimer's Disease Detection: All Errors are Equal, but Deletions are More Equal than Others

Balagopalan A., Shkaruta K., Novikova J. (2019)

W-NUT Workshop on Noisy User-generated Text at EMNLP 2020.

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Detecting Cognitive Impairments by Agreeing on Interpretations of Linguistic Features

Zhu Z., Novikova J., Rudzicz F. (2019)

NAACL 2019.

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The Effect of Heterogeneous Data for Alzheimer’s Disease Detection from Speech

Balagopalan A., Novikova J., Rudzicz F., Ghassemi M. (2018)

Machine Learning for Health Workshop at NeurIPS 2018.

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Semi-supervised Classification by Reaching Consensus Among Modalities

Zhu Z., Novikova J., Rudzicz F. (2018)

IRASL, Interpretability and Robustness in Audio, Speech and Language Workshop at NeurIPS 2018.

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Learning Multiview Embeddings for Assessing Dementia

Pou-Prom C., Rudzicz F. (2018)

Proceedings of Empirical Methods in Natural Languages Processing 2018.

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A Swedish Cookie-Theft Corpus

Kokkinakis D., Lundholm Fors K., Fraser K.C., Nordlund A. (2018)

Proceedings of the 11th edition of the Language Resources and Evaluation Conference (LREC). Miyazaki, Japan.

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On the Importance of Normative Data in Speech-based Assessment

Noorian Z., Pou-Prom C., Rudzicz F. (2017)

Machine Learning for Health Workshop at NIPS 2017.

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Rhetorical Structure and Alzheimer’s Disease

Abdalla M., Rudzicz F., Hirst G. (2017)

Aphasiology, 32(1):41-60.

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Identifying and Avoiding Confusion in Dialogue with People with Alzheimer’s Disease

Chinaei H., Danks A, Mehta T., Chan-Currie L., Lin H., Rudzicz F. (2017)

Computational Linguistics, 43(2):377-406.

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Speech Recognition in Alzheimer’s Disease and in its Assessment

Zhou L., Fraser K., Rudzicz F. (2016)

Proceedings of Interspeech 2016.

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Vector-space Topic Models for Detecting Alzheimer's Disease

Yancheva, M., Rudzicz, F. (2016)

Proceedings of the 54th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers).

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Toward Dementia Diagnosis via Artificial Intelligence

Rudzicz F. (2016)

Today’s Geriatric Medicine, 9(2):8, March.

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Linguistic features identify Alzheimer’s disease in narrative speech

Fraser K., Meltzer J., Rudzicz F. (2015)

Journal of Alzheimer's Disease, 49(2), 407-422.

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